Hair regrowth treatments have come a long way. While finasteride and topical minoxidil remain the foundation, oral minoxidil has emerged as the real game-changer — especially for the 30-40% of men who don't respond to topical treatment.
Below we compare providers, break down the oral vs topical minoxidil debate with actual clinical data, and help you understand what results to expect.
Provider Comparison
| Provider | Starting Price | Treatments | Oral Min? | Combos? | Action |
|---|---|---|---|---|---|
|
H
Hims
Editor's Choice
|
$16/mo
Finasteride only
|
Finasteride, Minoxidil (oral & topical), Biotin gummies, custom combos | Yes | Yes | Get Started |
|
K
Keeps
Hair loss specialist
|
$10/mo
Generic finasteride
|
Finasteride, Minoxidil (topical), Ketoconazole shampoo | Limited | Yes | Get Started |
|
Ro
Ro (Roman)
Full telehealth platform
|
$17/mo
Finasteride
|
Finasteride, Minoxidil (oral & topical), Dutasteride | Yes | Yes | Get Started |
|
HH
Happy Head
Custom formulas
|
$79/mo
Custom topical
|
Custom compounded topicals (Fin + Min + more), Oral options | Yes | Yes | Get Started |
* Prices as of December 2025. Oral minoxidil is prescribed off-label (not FDA-approved for hair loss). We may earn commissions from affiliate links.
Why Oral Minoxidil Is a Game-Changer
The biggest development in hair loss treatment since finasteride.
The Problem with Topical
Topical minoxidil fails for 30-40% of men. Why? It's a pro-drug that requires conversion by scalp enzymes (sulfotransferase) to become active. Many men simply don't have enough of this enzyme in their scalp.
No matter how religiously you apply it, if your scalp can't activate it, you'll see zero results. This is the "enzymatic bottleneck."
The Oral Solution
Oral minoxidil bypasses this completely. When you swallow it, your liver activates the drug (the liver has abundant sulfotransferase). The active form then travels via bloodstream to your follicles.
Result: It works regardless of your scalp enzyme status. Even "non-responders" to topical often see dramatic results with oral.
Clinical Data: Oral vs Topical
Sources: Penha et al. 2024 meta-analysis; Ramos et al. systematic review
Dosing (Men)
- • Starting: 1.25mg or 2.5mg daily
- • Standard: 2.5mg daily
- • Maximum: 5mg daily (higher side effects)
Timeline
- • Week 4-8: "Dread shed" (temporary, good sign)
- • Month 3-6: Visible improvement begins
- • Month 12+: Full results
Real Talk: The Body Hair Side Effect
Let's address the elephant in the room. Oral minoxidil causes hypertrichosis (increased body hair) in 15-93% of users depending on dose. Arms, chest, back, even ears.
Here's the thing: it's actually a sign the drug is working. If you're growing body hair, you're a responder. Only 0.5% of patients discontinue because of this.
Silver Lining for Some
There's a whole community of men who use oral minoxidil specifically for beard growth. If you've always wanted a fuller beard, this might be a welcome bonus. The same mechanism that regrows scalp hair works on facial follicles too.
Hair Growth Treatments Explained
Finasteride
Generic Propecia
Blocks DHT production (the hormone that miniaturizes follicles). Protects existing hair while allowing regrowth.
- Dose: 1mg daily
- Results: Maintains and regrows hair in 90%+ of men
- Side effects: Sexual (2-4%), reversible
- Cost: $10-20/month
Minoxidil (Topical)
Rogaine / Generic
Stimulates growth and extends growth phase. The "gas" that promotes regrowth.
- Dose: 5% solution, twice daily
- Results: Regrowth in 60-70% of responders
- Side effects: Scalp irritation (6%+)
- Cost: $15-30/month
Minoxidil (Oral)
Low-dose, off-label
Same drug, systemic delivery. Works even if topical failed. Once-daily convenience.
- Dose: 2.5-5mg daily (men)
- Results: Works in topical non-responders
- Side effects: Body hair (common), fluid retention (rare)
- Cost: $20-35/month
Combination Therapy
Finasteride + Minoxidil
The gold standard. Finasteride protects your hair, minoxidil accelerates growth. Maximum results from two angles.
- Options: Separate pills, or compounded chewables
- Results: Best outcomes in clinical studies
- Providers: Hims offers combo chewables
- Cost: $30-60/month bundled